Assessment of the Global, Regional, and National Impact of Pathogen-Related Infectious Diseases in Children by Age and Gender from 1990 to 2021: A Comprehensive Review

By
Xin Zhao
Zenghou Liu
Yanwei Wang
Yanhua Wang
Wendi Zhang
Xiaoxin Wang
Dalu Song
Zhuohui Zhao
Xin Liu
June 8, 2026

Infection

Objective:

To systematically evaluate the contributions of 34 major pathogens to pathogen-attributable deaths and disease burden in children aged 0–14 years, with projections extending to 2050.

Key Findings:

Interpretation:

Remove or rephrase to avoid unsupported conclusions.

Limitations:

The study relies on modeled estimates rather than direct laboratory-confirmed data.
Pathogen categories are not mutually exclusive, which may complicate interpretation of burden estimates.

Conclusion:

Revise to reflect only the findings without unsupported claims.

Sources:

Global Burden of Disease Study

Assessment of the Global, Regional, and National Impact of Pathogen-Related Infectious Diseases in Children by Age and Gender from 1990 to 2021: A Comprehensive Review

Objective:

Key Findings:

Interpretation:

Limitations:

Conclusion:

Sources:

Original Source(s)

Global, regional, and national burden of pathogen-attributable infectious diseases in children by age and sex, 1990–2021: a systematic analysis

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