Higher Area Deprivation Index scores predict incomplete pre-operative high-resolution manometry in Achalasia patients undergoing peroral endoscopic myotomy - Summary - MDSpire

Higher Area Deprivation Index scores predict incomplete pre-operative high-resolution manometry in Achalasia patients undergoing peroral endoscopic myotomy

  • By

  • Yassmin Hegazy

  • Mary Michael Shannon

  • Dylan Mcclain

  • Justin Labonte

  • Venkata Seerapu

  • Eldrin Bhanat

  • Salit Chakma

  • Fazlay Faruque

  • Jacob Moremen

  • July 9, 2026

  • 0 min

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Objective:

To examine the association between Area Deprivation Index (ADI) scores and rates of High-Resolution Manometry (HRM) completion and post-operative follow-up in Achalasia patients undergoing Peroral Endoscopic Myotomy (POEM).

Approach:
  • Study Design: Retrospective cohort study evaluating patients with Achalasia undergoing POEM from March 2017 to December 2024.
  • Inclusion/Exclusion Criteria: Included patients aged 18 or older who underwent POEM with a residential ZIP code; excluded those without a home address or with suppressed ADI scores.
  • ADI Measurement: Used 2023 ADI national rank scores to assess neighborhood socioeconomic status, with higher scores indicating greater deprivation.
  • Statistical Analysis: Multivariable logistic regression models evaluated factors associated with HRM completion and post-operative follow-up.
Key Findings:
  • Higher ADI scores were associated with lower rates of HRM completion.
  • Patients from more deprived neighborhoods had reduced rates of post-operative follow-up.
Interpretation:

Limitations:
  • The study is limited to a single institution, which may affect generalizability.
  • Potential confounding factors not included in the final model may influence outcomes.
Conclusion:

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