Objective:

To evaluate the association between the C-reactive protein-triglyceride-glucose index (CTI) and major adverse cardiovascular events (MACEs) following percutaneous coronary intervention (PCI), addressing the gap in existing research.

Key Findings:

• 459 participants experienced MACEs during the follow-up period.
• CTI levels significantly correlated with the incidence of adverse outcomes.
• CTI was identified as an independent predictor of MACEs.
• RCS analysis indicated a non-linear relationship between CTI and primary outcomes, and a linear relationship with secondary outcomes.

Interpretation:

Pre-PCI CTI levels are significantly associated with adverse outcomes, highlighting its potential role in clinical risk assessment.

Limitations:

• Retrospective design may introduce selection bias.
• Data collected from a single hospital may limit generalizability.
• Potential confounding factors or biases in the study were not fully addressed.

Conclusion:

CTI is a promising biomarker for predicting MACEs in patients undergoing PCI, emphasizing its importance in clinical practice.