Authors’ Reply: Beyond Visual Consensus: Tiered Reference Framework for AI Cystoscopy Studies
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By
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Chung-You Tsai
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Shi-Wei Huang
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June 18, 2026
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Objective:
To clarify the methodology regarding the reference standard used in the study on AI-driven cystoscopy.
Approach:
Key Findings:
- The final consensus diagnosis was based on both expert review and source-provided diagnostic information.
- The study aimed to evaluate model-generated cystoscopic interpretation rather than revalidate original pathological diagnoses.
Interpretation:
Histopathology remains the definitive standard for pathological lesion classification.
Limitations:
- The study does not independently re-establish or revalidate the original pathological diagnosis of each image.
Conclusion:
The study serves as an image interpretation and reasoning benchmark based on pre-existing diagnostic information.