To determine the prevalence of pulmonary vein stenosis (PVS) and identify donor- and recipient-related predictors in pediatric heart transplantation, emphasizing the importance of these predictors for patient outcomes.
Key Findings:
18% of recipients developed de novo PVS with a median time to diagnosis of 84 days among 50 patients.
Congenital heart disease (CHD) was significantly associated with PVS (p = 0.015; OR, 11.25).
PVS did not significantly affect survival probability (p = 0.240).
Interpretation:
PVS occurred predominantly in patients with CHD, highlighting the need for targeted surveillance, but findings are exploratory due to limited sample size.
Limitations:
Small sample size limits generalizability and the robustness of the findings.
Findings are exploratory and require validation in larger cohorts to confirm associations.
Conclusion:
Identification of high-risk groups for PVS is essential for surveillance and preventive strategies in pediatric heart transplantation, underscoring the need for further research.
