To study the impact of fibromyalgia on the frequency and severity of migraine headache attacks and the associated psychological distress in patients with comorbid migraine and fibromyalgia.
Key Findings:
Patients with comorbid migraine and fibromyalgia had significantly higher monthly migraine days (MMD), headache impact test-6 (HIT-6), and DASS-12 scores compared to migraine-only patients (p < 0.001 for MMD and DASS-12; p = 0.009 for HIT-6).
Positive correlations were found between FIQR total score and DASS-12 total score (p = 0.001), as well as between FIQR and both MMD (p = 0.002) and HIT-6 scores (p = 0.008).
DASS-12 total score also positively correlated with MMD (p = 0.006) and HIT-6 scores (p = 0.027).
Interpretation:
Fibromyalgia exacerbates migraine frequency and severity, contributing to increased psychological distress in affected patients.
Limitations:
The study was limited to female patients, which may affect generalizability to the broader population.
Exclusion of patients with other primary headaches or psychiatric disorders may limit the understanding of comorbidities and their effects.
Conclusion:
Fibromyalgia is an aggravating comorbid condition with migraine, associated with higher frequency and severity of migraine attacks and increased psychological burden, highlighting the need for targeted treatment strategies.
by Amr Hassan, Mona Hussein, Rehab Magdy, Anas Elgenidi, Nahla Merghany, Ahmed Yehia Ismaeel, Mohamed Abdelghaffar, Osama Yacoub, May M. Fayez, Nourhan Abdelmohsen Taha, Ramez Reda Moustafa, Ahmed Essmat
