Objective:

To evaluate the implementation and outcomes of a universal opt-in screening program for HIV, HBV, and HCV in an emergency department in Berlin, addressing the critical issue of late diagnoses.

Key Findings:

• The program aimed to increase early diagnosis of BBVs in a high-prevalence urban setting, with a focus on specific high-risk groups.
• Approximately 50,000 patient visits annually at the emergency department provided a significant opportunity for screening, with a notable increase in testing uptake.
• Late diagnoses of HIV were prevalent, particularly among specific high-risk groups, highlighting the need for targeted interventions.

Interpretation:

Implementing universal screening in emergency departments can enhance early detection of BBVs, potentially reducing transmission and healthcare costs, though challenges in patient engagement and follow-up must be addressed.

Limitations:

• The study was retrospective and may have biases related to data collection and patient selection.
• Only 29 non-continuous months of data were analyzed due to interruptions, which may affect the generalizability of the findings.

Conclusion:

A universal opt-in testing strategy in emergency departments can facilitate earlier diagnoses of HIV, HBV, and HCV, contributing to better health outcomes and public health efforts, particularly in addressing late diagnoses.