To synthesize the available human clinical evidence regarding magnetic compression anastomosis in gastrointestinal surgery, focusing on procedural feasibility, clinical outcomes, and potential complications.
Approach:
Study Design: A systematic review was conducted in accordance with PRISMA 2020 guidelines, with a registered protocol in the PROSPERO database.
Literature Search: A systematic search was performed across PubMed/MEDLINE, Embase, and the Cochrane Library from inception to May 2025 using specific search terms related to magnetic compression anastomosis.
Eligibility Criteria: Studies were included if they reported MCA use in human subjects for gastrointestinal surgeries and described at least one clinical outcome, excluding animal studies and non-clinical reports.
Quality Assessment: Study quality was assessed using MINORS criteria for cohort studies and CARE guidelines for case reports.
Key Findings:
Magnetic compression anastomosis avoids tissue penetration and foreign material, potentially reducing complications associated with traditional sutures and staples.
Early clinical applications have shown promise in various gastrointestinal surgeries, including bowel continuity restoration and management of congenital conditions.
The available evidence is limited to small case series and individual reports, with no comprehensive synthesis of human clinical data.
Interpretation:
The review highlights the potential of magnetic compression anastomosis as an alternative to conventional techniques, but emphasizes the need for more extensive clinical data.
Limitations:
The available evidence is limited to small case series and individual reports.
No comprehensive synthesis of human clinical data currently exists.
Conclusion:
Further research is needed to establish the efficacy and safety of magnetic compression anastomosis in gastrointestinal surgeries.