An evaluation of factors associated with hypertension in children and adolescents with obesity - Summary - MDSpire

An evaluation of factors associated with hypertension in children and adolescents with obesity

  • By

  • Zhou, Kexin

  • Cai, Zili

  • Xiang, Shiting

  • Wei, Jianhui

  • Deng, Manxin

  • Peng, Yunlong

  • Liu, Zhiyu

  • Tan, Jie

  • Zhu, Guanghui

  • Gong, Zhuo

  • Li, Qi

  • Zhu, Lemei

  • Qiu, Jun

  • April 30, 2026

  • 0 min

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Objective:

To identify hypertension risk factors in obese children and their relationships.

Key Findings:
  • The detection rate of hypertension in children with obesity was 20.6%.
  • The mean age of participants was 11.9±2.0 years.
  • Logistic regression indicated that neutrophils (NE), the ratio of neutrophils to lymphocytes (NLR), platelet count (PLT), albumin (ALB), and triglycerides (TG) were independent risk factors for hypertension.
  • NE, NLR, PLT, ALB, and TG showed a significant linear relationship with systolic blood pressure (SBP) and diastolic blood pressure (DBP).
  • A nonlinear dose-response relationship was observed between PLT and SBP, but not between PLT and DBP.
Interpretation:

Elevated levels of NE, NLR, PLT, ALB, and TG are associated with hypertension in children with obesity, suggesting potential targets for intervention.

Limitations:
Conclusion:

The study highlights specific hematological and biochemical markers that may serve as risk factors for hypertension in obese children, guiding future prevention strategies.

Original Source(s)

An evaluation of factors associated with hypertension in children and adolescents with obesity

  • by Zhou, Kexin , Cai, Zili , Xiang, Shiting , Wei, Jianhui , Deng, Manxin , Peng, Yunlong , Liu, Zhiyu , Tan, Jie , Zhu, Guanghui , Gong, Zhuo , Li, Qi , Zhu, Lemei , Qiu, Jun

  • April 30, 2026

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