Risk factors for refractory BPPV: subtype-dependent association of serum 25-hydroxyvitamin D - Summary - MDSpire

Risk factors for refractory BPPV: subtype-dependent association of serum 25-hydroxyvitamin D

  • By

  • Hye Ah Joo

  • Sun A. Han

  • Jin Kim

  • Il-Seok Park

  • Min Young Kwak

  • June 3, 2026

  • 0 min

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Objective:

To evaluate refractory BPPV based on the number of CRP attempts and investigate clinical factors associated with treatment resistance, with a focus on serum 25(OH)D levels and BPPV subtype.

Key Findings:
  • 27.5% of patients required three or more CRP attempts, defining them as refractory BPPV.
  • BPPV subtype and prior vestibular neuritis were strong predictors of treatment resistance.
  • Lower serum 25(OH)D levels were associated with refractoriness, particularly in typical BPPV.
Interpretation:

Limitations:
  • Study design is retrospective, which may introduce bias, affecting the reliability of the findings.
  • Exclusion of patients with central lesions limits generalizability.
Conclusion:

Original Source(s)

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