Postoperative Changes in Retinal Vessel Diameter and Optic Disc Morphology Following Glaucoma Surgery in Pediatric Patients: A Quantitative Analysis Using Fundus Photography - Summary - MDSpire
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Postoperative Changes in Retinal Vessel Diameter and Optic Disc Morphology Following Glaucoma Surgery in Pediatric Patients: A Quantitative Analysis Using Fundus Photography
Postoperatively, despite successful IOP reduction, major peripapillary veins and arteries remained abnormally narrow.
16.67% of patients exhibited notable cup reversal, correlated with inferior rim widening.
Preoperative disc hemorrhage and higher β-zone PPA Regularity Index were independent predictors of cup reversal.
Interpretation:
Surgery leads to a complex remodeling response in pediatric glaucoma, with some structural recovery of the optic cup but persistent narrowing of retinal vessels, suggesting maladaptive vascular changes.
Limitations:
Small sample size of 24 glaucomatous eyes may limit generalizability.
Short follow-up period of 2 years may not capture long-term changes in vessel diameter and optic disc morphology.
Conclusion:
Successful glaucoma surgery may induce partial optic cup reversal in some patients, but vascular changes appear to be maladaptive, indicating potential irreversible glaucomatous damage in children.
