Predictive value and correlation analysis of neutrophil-to-lymphocyte ratio for early prognosis in patients with intracerebral hemorrhage undergoing surgical treatment - Summary - MDSpire
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Predictive value and correlation analysis of neutrophil-to-lymphocyte ratio for early prognosis in patients with intracerebral hemorrhage undergoing surgical treatment
This study explored and quantified the early postoperative predictive value of NLR in surgically treated ICH patients.
Approach:
Method: label
Method: text
Key Findings:
The poor prognosis group had older age, lower admission Glasgow coma scale scores, larger hematoma volumes, and higher rates of intraventricular extension and midline shift (all p < 0.05), along with significantly higher NLR at all pre-operative and postoperative time points (all p < 0.001), the most prominent difference was in postoperative day 3 NLR (NLR-D3).
NLR-D3 showed the highest correlation with 30-day mRS (r = 0.847); its AUC for poor prognosis prediction was 0.802 (95%CI: 0.682, 0.922), with an optimal cut-off of 8.6 (85.3% sensitivity, 83.3% specificity).
Interpretation:
Early postoperative elevated NLR, especially on day 3, correlates closely with adverse outcomes in surgically treated ICH patients.
Limitations:
Study is retrospective and conducted at a single center.
Sample size may limit generalizability of findings.
Conclusion:
NLR-D3 correlates with short-term poor prognosis in surgically treated ICH patients.
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