Maternal Cardiovascular Health During Pregnancy and Offspring Developmental Delay - Summary - MDSpire

Maternal Cardiovascular Health During Pregnancy and Offspring Developmental Delay

  • By

  • Hisashi Ohseto

  • Mami Ishikuro

  • Geng Chen

  • Ippei Takahashi

  • Genki Shinoda

  • Aoi Noda

  • Keiko Murakami

  • Masatsugu Orui

  • Masato Takase

  • Noriyuki Iwama

  • Masahiro Kikuya

  • Hirohito Metoki

  • Atsushi Hozawa

  • Taku Obara

  • Shinichi Kuriyama

  • June 23, 2026

  • 0 min

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Objective:

To examine the association between maternal cardiovascular health during pregnancy, as assessed via Life’s Essential 8 (LE8), and developmental delay in offspring at 4 years of age.

Approach:
    Key Findings:
    • This study is the first to explore the association between maternal cardiovascular health during pregnancy and developmental delays in offspring.
    • Maternal cardiovascular health was assessed using the LE8 framework, which includes eight health metrics.
    • Developmental delay was defined as a score at least 2 SDs below the mean on the ASQ-3.
    Interpretation:

    Maternal cardiovascular health during pregnancy may serve as an important indicator of the intrauterine environment and long-term health outcomes for offspring.

    Limitations:
    • The study may have limitations related to self-reported data on maternal health metrics.
    • Exclusions of certain pregnancies may limit the generalizability of the findings.
    Conclusion:

    Further research is needed to establish a clear association between maternal cardiovascular health and developmental delays in offspring.

    Sources:

Original Source(s)

Maternal Cardiovascular Health During Pregnancy and Offspring Developmental Delay

  • by Hisashi Ohseto, Mami Ishikuro, Geng Chen, Ippei Takahashi, Genki Shinoda, Aoi Noda, Keiko Murakami, Masatsugu Orui, Masato Takase, Noriyuki Iwama, Masahiro Kikuya, Hirohito Metoki, Atsushi Hozawa, Taku Obara, Shinichi Kuriyama

  • June 23, 2026

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