Efficacy of the ‘Thinking Healthy Program’ in Alleviating Antenatal Depression Among Pregnant Women at a Tertiary Care Facility: A Quasi-Experimental Study Conducted in Pakistan - Summary - MDSpire

Efficacy of the ‘Thinking Healthy Program’ in Alleviating Antenatal Depression Among Pregnant Women at a Tertiary Care Facility: A Quasi-Experimental Study Conducted in Pakistan

  • By

  • Quratulain Ahsan

  • Javeria Saleem

  • Abid Malik

  • Rubeena Zakar

  • Kashif Siddique

  • Mahwish Naz

  • Gul Mehar Javaid Bukhari

  • Florian Fischer

  • April 18, 2026

  • 0 min

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Objective:

To determine the effectiveness of the Thinking Healthy Programme (THP) in reducing depressive symptoms among pregnant women in a tertiary care setting in Pakistan, specifically targeting those in their second trimester.

Key Findings:
  • The THP significantly reduced depressive symptoms in participants compared to baseline scores, with statistical significance.
  • The intervention was well-received and feasible in a tertiary care setting.
  • Improved maternal mental health is linked to better outcomes for both mothers and infants.
Interpretation:

The findings suggest that the THP is an effective intervention for alleviating antenatal depression, addressing a critical gap in mental health care in LMICs and highlighting the need for policy changes.

Limitations:
  • The study was conducted in a single tertiary care facility, limiting generalizability.
  • Follow-up duration was short, focusing only on immediate postpartum outcomes, and potential biases in participant selection were not addressed.
Conclusion:

The Thinking Healthy Programme is a promising intervention for reducing antenatal depression in Pakistan, underscoring the urgent need for integrating mental health services into routine antenatal care.

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