Is surgery with curative intent feasible in old and very old patients with non-small cell lung cancer? – Experience of a certified lung cancer center over one decade - Summary - MDSpire
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Is surgery with curative intent feasible in old and very old patients with non-small cell lung cancer? – Experience of a certified lung cancer center over one decade
To analyze the safety and efficacy of surgical treatment for non-small cell lung cancer (NSCLC) in elderly patients with curative intent.
Key Findings:
Out of 1680 patients, 1221 met inclusion criteria for the study.
Length of hospital stay increased with age, significantly longer in older patients (p < 0.001).
Cardiac arrhythmias were the only comorbidity significantly more common postoperatively in older patients (p = 0.02).
Overall survival was significantly poorer for patients aged over 80 compared to those aged 60 to 69, highlighting the need for careful age consideration.
Progression-free survival was not significantly associated with age.
Interpretation:
Surgery with curative intent is feasible for elderly patients with NSCLC, with comparable oncological outcomes; however, individual patient selection based on age and comorbidities is recommended for optimal outcomes.
Limitations:
Data from the study is still being analyzed and cannot be disclosed at this time, which may affect the interpretation of results.
Further studies are ongoing, limiting the availability of comprehensive data.
Conclusion:
Curative surgery for NSCLC is viable in elderly patients, but careful consideration of age and comorbidities is essential for optimal outcomes.
by Julia Zimmermann, Julia Walter, Nicole Samm, Fuad Damirov, Niels Reinmuth, Diego Kauffmann-Gerrero, Rudolf A. Hatz, Amanda Tufman, Christian P. Schneider
