Association between neurodegenerative plasma biomarkers and geriatric depression in older adults with and without clinical dementia in Kinshasa, Democratic Republic of the Congo - Summary - MDSpire

Association between neurodegenerative plasma biomarkers and geriatric depression in older adults with and without clinical dementia in Kinshasa, Democratic Republic of the Congo

  • By

  • Nathan Tsengele

  • Alfred Sodi Magudigana

  • Guy Gikelekele

  • Emmanuel Epenge

  • Guy Kangula

  • Eric Muteba Vukumuna

  • Abraham Mifundu Bilongo

  • Said Mbuku Nguala

  • Degani Banzulu Bomba

  • Gilbert Mananga Lelo

  • Adelin N’situ Mankubu

  • Jean Ikanga

  • May 22, 2026

  • 0 min

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Objective:

To examine the association between neurodegenerative plasma biomarkers and geriatric depression in older adults in Kinshasa, Democratic Republic of Congo.

Key Findings:
  • Participants with dementia had significantly lower cognitive scores compared to those without dementia.
Interpretation:

Limitations:
  • The study's cross-sectional design limits causal inferences.
  • Sample size may not be representative of the broader population.
Conclusion:

This research contributes to understanding the relationship between neurodegenerative biomarkers and depression in a sub-Saharan African context.

Original Source(s)

Association between neurodegenerative plasma biomarkers and geriatric depression in older adults with and without clinical dementia in Kinshasa, Democratic Republic of the Congo

  • by Nathan Tsengele, Alfred Sodi Magudigana, Guy Gikelekele, Emmanuel Epenge, Guy Kangula, Eric Muteba Vukumuna, Abraham Mifundu Bilongo, Said Mbuku Nguala, Degani Banzulu Bomba, Gilbert Mananga Lelo, Adelin N’situ Mankubu, Jean Ikanga

  • May 22, 2026

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