Combining Machine Learning Models and Screening to Enhance Suicide Risk Identification for American Indian Patients: Retrospective Cohort Study - Summary - MDSpire

Combining Machine Learning Models and Screening to Enhance Suicide Risk Identification for American Indian Patients: Retrospective Cohort Study

  • By

  • Novalene Alsenay Goklish

  • Emily E Haroz

  • Rohan R Dayal

  • Valentín Q Sierra

  • Roy Adams

  • Francene Larzelere Sinquah

  • Paul Rebman

  • Jacob L Taylor

  • May 11, 2026

  • 0 min

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Objective:

To evaluate the integration of a machine learning (ML) suicide risk model with the ASQ screening tool in emergency department (ED) visits among American Indian populations, addressing the urgent need for effective prevention strategies.

Key Findings:
  • The ML model achieved an AUROC of 0.83 for predicting suicide attempts or deaths within 90 days, indicating strong predictive capability.
  • Parallel testing strategies identified more at-risk individuals compared to screening alone, enhancing early intervention opportunities.
  • Serial testing strategies reduced false positives but risked missing some at-risk individuals, highlighting a trade-off in risk assessment.
Interpretation:

Integrating ML models with existing screening practices can enhance suicide risk identification in American Indian populations, potentially improving prevention efforts, though challenges in integration must be addressed.

Limitations:
  • The study is retrospective and may not account for all variables influencing suicide risk, which could affect the reliability of the findings.
  • Limited generalizability to other populations outside American Indian communities may restrict the applicability of the results.
Conclusion:

Combining ML models with traditional screening tools may optimize suicide risk assessment and improve clinical workflows in emergency settings, emphasizing the need for culturally tailored approaches.

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