Guillain-Barré syndrome presenting with abdominal pain as the initial manifestation: a case report - Summary - MDSpire

Guillain-Barré syndrome presenting with abdominal pain as the initial manifestation: a case report

  • By

  • Zi-Zhen Yin

  • Yu Liu

  • June 11, 2026

  • 0 min

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Objective:

To describe a rare case of Guillain-Barré syndrome (GBS) presenting with abdominal pain as the initial manifestation, highlighting the diagnostic challenges and implications for clinical practice.

Approach:
    Key Findings:
    • GBS can present with abdominal pain as an initial symptom, which is uncommon.
    • The patient was initially misdiagnosed with acute cholecystitis but later exhibited characteristic symptoms of GBS.
    • Diagnostic challenges arise when GBS presents atypically, potentially delaying appropriate treatment; specific examples of these challenges should be included.
    Interpretation:

    Abdominal pain may precede neurological symptoms in GBS, necessitating a high index of suspicion for GBS in patients with abdominal pain and rapid neurological decline. Further research is recommended to explore this atypical presentation.

    Limitations:
    • This is a single case study, limiting generalizability.
    • The atypical presentation may not be representative of all GBS cases, and potential biases in case reporting should be acknowledged.
    Conclusion:

    Physicians should consider GBS in patients presenting with abdominal pain and neurological deterioration, emphasizing the need for increased awareness and prompt diagnostic evaluation.

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