Women and Dry Eye - Summary - MDSpire

Women and Dry Eye

  • By

  • Deborah Fisher

  • June 17, 2026

  • 3 min

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Objective:

To highlight the impact of hormonal status and cosmetic use on dry eye disease in women.

Approach:
    Key Findings:
    • Women are twice as likely as men to develop clinically significant dry eye disease (DED).
    • Hormonal changes, particularly declining estrogen, progesterone, and androgen levels, are major contributors to dry eye, with testosterone deficiency linked to evaporative dry eye.
    • Cosmetic practices, such as tightlining eyeliner, waterproof makeup, and eyelash extensions, can exacerbate ocular surface disease and destabilize the tear film.
    • A gender-sensitive history improves diagnostic accuracy and treatment outcomes, as hormonal status and cosmetic use can significantly affect test results.
    • Management strategies should be personalized and consider hormonal influences, with recommendations varying by life stage.
    Interpretation:

    Successful diagnosis and management of dry eye in women require consideration of hormonal history and cosmetic habits.

    Limitations:
    • The presentation may not cover all potential factors influencing dry eye disease.
    • Further research may be needed to establish comprehensive management protocols.
    Conclusion:

    Incorporating hormonal and aesthetic considerations into clinical practice is essential for effective dry eye management in women.

    Sources:

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