Impact of Hospice Care Plus Estazolam on Sleep and Psychological Distress in Advanced Gastrointestinal Cancer: A Real-World Observational Study - Summary - MDSpire
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Impact of Hospice Care Plus Estazolam on Sleep and Psychological Distress in Advanced Gastrointestinal Cancer: A Real-World Observational Study
To retrospectively evaluate the effects of hospice care combined with estazolam on sleep quality and psychological status in patients with advanced gastrointestinal cancer.
Key Findings:
The hospice-care plus estazolam group showed significant improvements in sleep quality (PSQI, P < .001), anxiety (SAS, P < .001), and depression (SDS, P < .001).
Cohen's d for sleep quality was large (d = 1.15), indicating substantial effect sizes.
The ESAS appetite subscale showed a moderate-to-large effect (Cohen's d = 0.758), while other ESAS and QLQ-C30 subscales had Cohen's d values above 1.0.
Interpretation:
The combined treatment of hospice care and estazolam is associated with significant clinical improvements in sleep, psychological state, and overall quality of life in patients with advanced gastrointestinal cancer.
Limitations:
Conclusion:
This retrospective analysis suggests that hospice care combined with estazolam is associated with significantly better sleep quality, psychological well-being, and overall quality of life in patients compared to routine nursing with estazolam alone.
