COVID-19-specific risk factor for early post-appendectomy complications (EPAC) in older patients: a retrospective study - Summary - MDSpire

COVID-19-specific risk factor for early post-appendectomy complications (EPAC) in older patients: a retrospective study

  • By

  • Tamer A. A. M. Habeeb

  • A. Hussain

  • Jose Bueno-Lledó

  • M. E. Giménez

  • A. Aiolfi

  • M. Chiaretti

  • I. A. Kryvoruchko

  • M. N. Manangi

  • Abd Al-Kareem Elias

  • Abdelmonem A.M Adam

  • Mohamed A. Gadallah

  • Saad Mohamed Ali Ahmed

  • Ahmed Khyrallh

  • Mohammed H. Alsayed

  • Esmail Tharwat Kamel Awad

  • Emad A. Ibrahim

  • Mohammed Hassan Elshafey

  • Mohamed fathy Labib

  • Mahmoud Hassib Morsi Badawy

  • Sobhy rezk ahmed Teama

  • Abdelhafez Seleem

  • Mohamed Ibrahim Abo Alsaad

  • Abouelatta KH Ali

  • Hamdi Elbelkasi

  • Mahmoud Ali abou zaid

  • Basma Ahmed Mohamed

  • Alaa Alwadees

  • Ahmed k. El-Taher

  • Mohamed Ibrahim Mansour

  • Mahmoud Abdou Yassin

  • Ahmed Salah Arafa

  • Mohamed Lotfy

  • Baher Atef

  • Mohamed Elnemr

  • Mostafa M Khairy

  • Abdelfatah H. Abdelwanis

  • ahmed mesbah Abdelaziz

  • Abdelshafy Mostafa

  • AbdElwahab M. Hamed

  • Tamer Wasefy

  • Ibrahim A. Heggy

  • Abdelrahman Mohamed Hasanin Nawar

  • November 5, 2025

  • 0 min

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Objective:

To evaluate the incidence and risk factors associated with early post-appendectomy complications (EPAC) in older patients during and after the COVID-19 pandemic, specifically from April 2020 to December 2024.

Key Findings:
  • Older patients often present with atypical symptoms leading to diagnostic delays.
  • The incidence of severe acute appendicitis is higher in older patients, with perforation rates approaching 70%.
  • COVID-19 infection during surgery may be a risk factor for EPAC, with a need for quantification of this risk.
Interpretation:

The study highlights the increased risk of complications in older patients undergoing appendectomy during the COVID-19 pandemic, emphasizing the need for tailored surgical approaches, careful patient management, and consideration of implications for clinical practice.

Limitations:
  • Retrospective design may introduce selection bias.
  • Limited generalizability due to the study being conducted in specific tertiary centers, and potential confounding factors should be acknowledged.
Conclusion:

The findings underscore the importance of recognizing COVID-19 as a potential risk factor for early complications in older patients undergoing appendectomy, necessitating further research and refined surgical protocols, particularly in diverse healthcare settings.

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