To evaluate the efficacy and safety of various Chinese herbal decoctions in breast cancer treatment through a network meta-analysis.
Approach:
Literature Search: A systematic search was conducted across multiple databases for randomized controlled trials comparing the efficacy and safety of different Chinese herbal decoctions in breast cancer patients.
Quality Assessment: Quality assessment was performed using the Risk of Bias 2.0 tool.
Data Analysis: Network meta-analysis was conducted using R 4.5.1.
Key Findings:
YHHYT decoction showed a significant objective response rate with an OR of 4.76.
BZT decoction demonstrated the highest disease control rate with an OR of 5.77.
FJHQT decoction achieved a significant increase in CD4+/CD8+ ratio with an MD of 0.69.
BZT decoction ranked first in relieving nausea and vomiting with an OR of 0.25.
Interpretation:
Limitations:
Clinical heterogeneity and non-uniform treatment protocols across studies.
Insufficient sample sizes in some trials.
Conclusion:
The network meta-analysis provides evidence supporting the therapeutic effects of Chinese herbal decoctions in breast cancer treatment.
