Influence of left ventricular ejection fraction on the clinical outcome of percutaneous coronary interventions in heart transplant patients - Summary - MDSpire
To assess whether pre-procedural left ventricular ejection fraction (LVEF) is associated with outcomes after percutaneous coronary intervention (PCI) in heart transplant recipients.
Approach:
Design and population: Retrospective single-center analysis of adult heart transplant recipients who underwent PCI from January 2011 through June 2023; each patient was included once, at their first PCI.
Groups and follow-up: Patients were grouped by pre-PCI LVEF as preserved (>50%) or reduced (≤50%). Outcomes were assessed during hospitalization and through a maximum of three years.
Outcomes and analysis: The primary endpoint was all-cause mortality. Secondary endpoints included mortality and MACCE, defined as death, myocardial infarction, stroke, or target-vessel/target-lesion revascularization. Multivariable analyses adjusted for age, eGFR, hemoglobin, BMI, r…
Key Findings:
The cohort included 159 recipients: 107 (67.3%) had LVEF >50% and 52 (32.7%) had LVEF ≤50%.
Recipients with LVEF ≤50% were younger on average than those with LVEF >50% (54.13 ± 15.65 vs 59.34 ± 14.98 years).
The provided article context ends before reporting clinical outcome results; associations between LVEF and mortality or MACCE are therefore not available.
Interpretation:
The supplied context describes the study design and initial baseline findings but does not provide results sufficient to determine how LVEF related to post-PCI outcomes.
Limitations:
The supplied context is incomplete and does not include the full results or discussion.
The study was a retrospective analysis from a single center.