Influence of left ventricular ejection fraction on the clinical outcome of percutaneous coronary interventions in heart transplant patients - Summary - MDSpire
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Impact of Left Ventricular Ejection Fraction on Outcomes Following Percutaneous Coronary Interventions in Heart Transplant Recipients

  • By

  • Luisa Elbinger

  • Tobias Schupp

  • Michael Behnes

  • Ibrahim Akin

  • Angelika Costard-Jäckle

  • Rene Schramm

  • Tanja Rudolph

  • Volker Rudolph

  • Mohamed Ayoub

  • October 7, 2026

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Objective:

To assess whether pre-procedural left ventricular ejection fraction (LVEF) is associated with outcomes after percutaneous coronary intervention (PCI) in heart transplant recipients.

Approach:
  • Design and population: Retrospective single-center analysis of adult heart transplant recipients who underwent PCI from January 2011 through June 2023; each patient was included once, at their first PCI.
  • Groups and follow-up: Patients were grouped by pre-PCI LVEF as preserved (>50%) or reduced (≤50%). Outcomes were assessed during hospitalization and through a maximum of three years.
  • Outcomes and analysis: The primary endpoint was all-cause mortality. Secondary endpoints included mortality and MACCE, defined as death, myocardial infarction, stroke, or target-vessel/target-lesion revascularization. Multivariable analyses adjusted for age, eGFR, hemoglobin, BMI, r…
Key Findings:
  • The cohort included 159 recipients: 107 (67.3%) had LVEF >50% and 52 (32.7%) had LVEF ≤50%.
  • Recipients with LVEF ≤50% were younger on average than those with LVEF >50% (54.13 ± 15.65 vs 59.34 ± 14.98 years).
  • The provided article context ends before reporting clinical outcome results; associations between LVEF and mortality or MACCE are therefore not available.
Interpretation:

The supplied context describes the study design and initial baseline findings but does not provide results sufficient to determine how LVEF related to post-PCI outcomes.

Limitations:
  • The supplied context is incomplete and does not include the full results or discussion.
  • The study was a retrospective analysis from a single center.

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