To investigate the relationship between the serum ApoB/ApoA-I ratio and intracranial atherosclerotic stenosis (ICAS) in young adults with ischemic stroke.
Key Findings:
Higher prevalence of diabetes mellitus, smoking, and hyperlipidemia in ICAS group.
Increased levels of ApoB and ApoB/ApoA-I ratio in ICAS group compared to non-ICAS group.
Lower levels of HDL-C and ApoA-I in ICAS group.
Dose-response relationship between ApoB/ApoA-I ratio quartiles and ICAS risk.
Interpretation:
A higher ApoB/ApoA-I ratio is independently associated with ICAS in young ischemic stroke patients, suggesting it may be a significant risk factor.
Limitations:
Findings need confirmation through vessel wall imaging in future studies.
Study limited to a specific age group (18-45 years).
Conclusion:
The ApoB/ApoA-I ratio may serve as a potential biomarker for assessing ICAS risk in young adults experiencing ischemic stroke.
