To assess the association between the time from symptom onset to minimally invasive puncture and drainage (MIPD) and long-term mortality in patients with spontaneous intracerebral hemorrhage (sICH), highlighting its significance in improving patient outcomes.
Key Findings:
Long-term mortality rates were higher for MIPD within 6 h (48.48%) and 6 to 12 h (50.56%) compared to 12 to 24 h (30.34%) with p = 0.02, indicating statistical significance.
IPTW analysis indicated that MIPD within 12–24 h was associated with reduced short-term (OR 0.519) and long-term mortality (OR 0.530), both p = 0.03.
Interpretation:
Delaying MIPD to 12–24 hours post-symptom onset may improve long-term survival in patients with sICH, suggesting a need for timely intervention.
Limitations:
Retrospective design may introduce selection bias.
Single-center data may limit generalizability.
Potential confounding factors not addressed in the study.
Conclusion:
MIPD performed within 12 to 24 hours of symptom onset is associated with a decreased risk of long-term mortality in patients with sICH, emphasizing the critical nature of timing in treatment.
