New Research Sheds Light on How Precancerous Lesions Form in the Pancreas - Summary - MDSpire
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New Research Sheds Light on How Precancerous Lesions Form in the Pancreas

  • May 11, 2026

  • 3 min

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Research led by Dr. Megan Radyk at Roswell Park reveals insights into pancreatic cancer prevention through the study of metabolic enzymes. Published in Nature Metabolism, the preclinical study shows that impaired functions of glucose-6-phosphate dehydrogenase (G6PD) and malic enzyme 1 (ME1) are linked to the progression of precancerous lesions in the pancreas, which could enable early detection and intervention strategies. Understanding these metabolic changes may ultimately help identify biomarkers and therapeutic approaches to combat this aggressive cancer.

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