A need for bedside surrogates of ventriculoarterial coupling in critical care – can MAPSE be of help? - Summary - MDSpire
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Exploring the Role of MAPSE as a Bedside Indicator for Ventriculoarterial Coupling in Critical Care Settings

  • By

  • Jinyang Yu

  • October 5, 2026

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Objective:

To investigate the potential of Mitral Annular Plane Systolic Excursion (MAPSE) as a bedside surrogate for monitoring ventriculoarterial (VA) coupling in critically ill patients.

Approach:
  • Study Review: The article reviews findings from Valenzuela et al. regarding the unpredictability of VA coupling responses in critically ill patients and the inadequacy of conventional assessment methods.
  • Correlation Analysis: Exploratory analysis of correlations between MAPSE and non-invasive VA coupling estimates using both manual and AI-based approaches.
Key Findings:
  • VA coupling responses correlate weakly with changes in cardiac output, stroke volume, and left ventricular ejection fraction, as reported by Valenzuela et al.
  • MAPSE has been validated and is recognized in critical care guidelines according to Cavefors et al.
  • Cavefors et al. reported that MAPSE showed strong prognostic value in critically ill patients, potentially exceeding that of left ventricular ejection fraction and global longitudinal strain.
  • Correlations between MAPSE and VA coupling estimates were found (rho = -0.73 for manual calipers, rho = -0.61 for AutoMAPSE) in exploratory analyses.
Limitations:
  • Current findings require confirmation through additional analyses as noted in the source material.
  • Clinical implementation of MAPSE needs to clarify how it can direct and track therapeutic effects, as highlighted by Cavefors et al.
Conclusion:

Further exploratory analyses are needed to assess the concordance of MAPSE changes with VA coupling and other hemodynamic parameters, as suggested by Valenzuela et al.

Sources:

Original Source(s)

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