The association of adolescent to midlife weight change with age at natural menopause: a population study of 263 586 women in Norway - Summary - MDSpire
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The association of adolescent to midlife weight change with age at natural menopause: a population study of 263 586 women in Norway
To study associations of weight change from adolescence to midlife with the timing of natural menopause.
Key Findings:
Women with the largest weight loss had the highest hazard of reaching menopause (adjusted HR = 1.11; 95% CI, 1.06-1.17).
Women with the largest weight gain had a lower hazard of reaching menopause (adjusted HR = 0.96; 95% CI, 0.93-0.99).
Women with stable high weight had the lowest hazard of reaching menopause (adjusted HR = 0.93; 95% CI, 0.90-0.95).
Interpretation:
Weight changes throughout life may significantly influence the timing of menopause, suggesting that weight management is crucial for women's health.
Limitations:
Self-reported weight data may introduce bias.
The study did not include a specific question about time since the final menstrual period.
Findings may not be generalizable to populations outside Norway.
Conclusion:
Changes in body weight across the life course may influence the timing of menopause, highlighting the importance of weight management in women's health.
