A super-elderly patient with distal biliary tract cancer and tumor-associated granuloma: a case report - Summary - MDSpire

A super-elderly patient with distal biliary tract cancer and tumor-associated granuloma: a case report

  • By

  • Longfei Chen

  • Rong Ran

  • Jing Wu

  • Futang Li

  • Zikai Wei

  • Zhiwei He

  • Chao Yu

  • July 3, 2026

  • 0 min

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Objective:

To report a rare case of a 90-year-old female patient with distal cholangiocarcinoma (dCCA) who underwent surgical management.

Approach:
  • Patient Presentation: A 90-year-old woman presented with upper abdominal pain and distension. Imaging suggested a mass in the head of the pancreas.
  • Surgical Intervention: After a thorough preoperative assessment, the patient underwent pancreaticoduodenectomy, which confirmed poorly differentiated cholangiocarcinoma with negative margins.
  • Postoperative Management: Post-surgery, the patient received volume management and supportive treatment, experiencing transient cardiac stress and a fungal infection, both of which were managed.
Key Findings:
  • The patient had poorly differentiated cholangiocarcinoma with negative margins and no lymph node metastasis.
  • Non-caseating granulomas were observed, interpreted as tumor-related granulomatous reactions.
Interpretation:

The case highlights the potential for successful surgical intervention in elderly patients with dCCA, emphasizing the need for careful preoperative evaluation.

Limitations:
  • Limited evidence on the management of elderly patients with dCCA due to underrepresentation in clinical trials.
  • The rarity of tumor-associated granulomatous reactions complicates understanding and management.
Conclusion:

This case suggests that with appropriate evaluation and management, radical surgery can be safely performed in elderly patients with dCCA.

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