Effectiveness of an Embedded Infectious Disease Screening, Treatment, and Prevention Intervention Within an Inpatient Substance Use Treatment Program - Summary - MDSpire

Effectiveness of an Embedded Infectious Disease Screening, Treatment, and Prevention Intervention Within an Inpatient Substance Use Treatment Program

  • By

  • Kelly E Dyer

  • Rebecca Russell

  • Rayek Nafiz

  • Angela Burdick-McPhee

  • Jean O’Neal

  • Tanajsia Mason

  • Danica Kuncio

  • Hannah Zellman

  • Margaret Lowenstein

  • Nancy Aitcheson

  • Vincent Lo Re

  • Jessie Torgersen

  • July 24, 2025

  • 0 min

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Objective:

To evaluate the effectiveness of comprehensive infectious disease (ID) screening integrated within an inpatient substance use disorder (SUD) treatment program, addressing barriers to care.

Key Findings:
  • Screening for ≥1 ID increased from 60.2% in usual care to 90.8% in the intervention group (P < .001).
  • Vaccination rates for HAV and HBV rose significantly from 0% to 58% and 71%, respectively.
  • 36.8% of patients in the intervention group initiated direct-acting antiviral therapy for HCV within 2 weeks of testing, compared to 0% in usual care.
  • STIs were identified in 13.5% of the intervention group versus 9.2% in usual care (P = .09), indicating a trend towards increased identification.
Interpretation:

Integrating comprehensive ID screening within inpatient SUD programs significantly enhances testing uptake and facilitates timely preventive and therapeutic interventions.

Limitations:
  • The study was conducted at a single site, which may limit generalizability.
  • Only the first hospitalization was included for patients with multiple admissions, potentially affecting the data.
  • Lack of long-term follow-up data on patient outcomes.
Conclusion:

Comprehensive ID screening within inpatient SUD programs can effectively increase testing rates and improve access to preventive and therapeutic care for infectious diseases, suggesting a need for further research in diverse settings.

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