Estimation of histopathological types from breast MRI findings using a large language model - Summary - MDSpire

Estimation of histopathological types from breast MRI findings using a large language model

  • By

  • Rie Kanasaki

  • Kazufumi Suzuki

  • Takami Ota

  • Sadako Akashi-Tanaka

  • Yoji Nagashima

  • Shuji Sakai

  • April 14, 2026

  • 0 min

Share

Objective:

To investigate whether a large language model (LLM) can accurately predict histopathological types of breast cancer based on imaging findings from contrast-enhanced breast MRI reports.

Key Findings:
  • 180 cases were included, resulting in 186 lesions analyzed.
  • Pathological results classified into 10 histopathological diagnoses.
  • LLM's predictions were assessed against pathology reports for accuracy.
Interpretation:

The study explores the potential of LLMs to bridge imaging findings and histopathological diagnoses, which could enhance reporting quality and facilitate research.

Limitations:
  • Retrospective design may introduce bias.
  • Exclusion of certain cases limits generalizability.
  • The LLM's predictions were not based on pathology report text.
Conclusion:

The ability of LLMs to predict histopathological types from MRI findings represents a promising step towards integrating AI into radiology workflows, though further validation is needed.

Original Source(s)

Related Content