Guiding Principles for Physician-Modified Endografts - Summary - MDSpire

Guiding Principles for Physician-Modified Endografts

  • By

  • Emiel W. M. Huistra

  • Clark J. Zeebregts

  • Robert C. Lind

  • July 10, 2026

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Objective:

To propose guiding principles for the practice of physician-modified endografts (PMEG) in aortic repair.

Approach:
  • Specialized Aortic Centers: PMEG should be performed in high-volume aortic centers with sufficient expertise and capability to manage complications.
  • Training and Proctoring: Dedicated training and proctoring are essential for operators starting a PMEG program or changing techniques.
  • Reproducible Methods: PMEG planning and modifications should rely on reproducible methods supported by the best available evidence.
  • Experimental Validation: Novel PMEG techniques should undergo appropriate experimental validation before clinical implementation.
Key Findings:
  • PMEG allows for patient-specific modifications of endografts in urgent situations.
  • There is significant variability in PMEG practices.
  • Correct fenestration positioning is critical for successful outcomes, and templates are recommended for guidance.
  • Training and proctoring improve safety and efficacy during the learning curve of PMEG procedures.
Interpretation:

PMEG represents a flexible approach to aortic repair but requires careful planning, training, and adherence to evidence-based practices.

Limitations:
  • Variability in regulations and resources may affect the implementation of standardized practices.
  • Lack of consensus on optimal reinforcement strategies for fenestrations.
Conclusion:

PMEG is a promising alternative for complex aortic repairs, but it necessitates specialized training and adherence to best practices to ensure patient safety and procedural success.

Sources:

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