Co-infection with Hepatitis Delta Virus in Hepatocellular Carcinoma Patients and HIV-Positive Individuals in Nigeria - Summary - MDSpire

Co-infection with Hepatitis Delta Virus in Hepatocellular Carcinoma Patients and HIV-Positive Individuals in Nigeria

  • By

  • Ijeoma Ifeorah

  • Birgit Bremer

  • Yusuf Musa

  • Julia Kahlhöfer

  • Oluwatosin Oguntoye

  • Carey Tishiya

  • Gatuwa Aglavdawa

  • Ojonuga Ameh

  • Yussuf Abdulkadir

  • Olumuyiwa Ariyo

  • Manfred Anim

  • Andre Reinhardt

  • Albert Heim

  • Uwem George

  • Lukman Abdulkareem

  • Ibrahim Umar Garzali

  • Heiner Wedemeyer

  • Lisa Sandmann

  • February 26, 2026

  • 0 min

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Objective:

To investigate HDV infection across diverse HBV-positive populations in Nigeria, specifically focusing on individuals with HCC, those co-infected with HIV, and asymptomatic chronic carriers.

Key Findings:
  • The prevalence of anti-HDV among HBV-infected individuals in Nigeria is under-researched and varies regionally, highlighting the need for targeted studies.
  • A total of 390 participants were tested, revealing significant rates of HDV co-infection in HBV-positive populations, which poses a public health concern.
  • HDV remains a neglected clinical issue in Nigeria, with limited awareness and testing facilities, necessitating urgent action.
Interpretation:

The study highlights the urgent need for improved surveillance and clinical management of HDV in Nigeria, particularly among high-risk groups, and suggests potential strategies for implementation.

Limitations:
  • Limited sample size and regional representation may affect the generalizability of findings, potentially skewing the understanding of HDV prevalence.
  • Lack of routine HDV testing in healthcare facilities hampers accurate prevalence estimation, emphasizing the need for policy changes.
Conclusion:

HDV co-infection is prevalent among HBV-infected individuals in Nigeria, necessitating enhanced diagnostic and treatment strategies to improve patient outcomes.

Original Source(s)

Co-infection with Hepatitis Delta Virus in Hepatocellular Carcinoma Patients and HIV-Positive Individuals in Nigeria

  • by Ijeoma Ifeorah, Birgit Bremer, Yusuf Musa, Julia Kahlhöfer, Oluwatosin Oguntoye, Carey Tishiya, Gatuwa Aglavdawa, Ojonuga Ameh, Yussuf Abdulkadir, Olumuyiwa Ariyo, Manfred Anim, Andre Reinhardt, Albert Heim, Uwem George, Lukman Abdulkareem, Ibrahim Umar Garzali, Heiner Wedemeyer, Lisa Sandmann

  • February 26, 2026

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