Validation of 2 Syncope Risk Scores and Comparison With Physician Risk Estimation - Summary - MDSpire

Validation of 2 Syncope Risk Scores and Comparison With Physician Risk Estimation

  • By

  • Edward H. Suh

  • Carolyn Winskill

  • Dana L. Sacco

  • John DeAngelis

  • Daniel K. Nishijima

  • Jonathan Schimmel

  • Alan B. Storrow

  • Nancy E. Wood

  • Venkatesh Thiruganasambandamoorthy

  • Christopher W. Baugh

  • Robert E. Weiss

  • Marc A. Probst

  • May 19, 2026

  • 0 min

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Objective:

To prospectively validate the Canadian Syncope Risk Score (CSRS) and FAINT score for predicting 30-day serious outcomes in patients aged 40 and older presenting with syncope or presyncope, and to compare their performance with physician risk evaluations.

Key Findings:
  • CSRS and FAINT score were validated for predicting serious outcomes within 30 days.
  • Physician risk estimates were compared to the scores for performance evaluation.
  • The study aimed for a sample size of 1232 patients to ensure adequate power for statistical analysis.
Interpretation:

The validation of CSRS and FAINT score could enhance risk stratification and management of patients with syncope and presyncope, potentially reducing unnecessary hospitalizations.

Limitations:
  • The study was limited to patients aged 40 and older.
  • Results may not be generalizable to all emergency department populations.
Conclusion:

Prospective validation of CSRS and FAINT score may provide objective tools for assessing risk in syncope patients, improving clinical decision-making.

Original Source(s)

Validation of 2 Syncope Risk Scores and Comparison With Physician Risk Estimation

  • by Edward H. Suh, Carolyn Winskill, Dana L. Sacco, John DeAngelis, Daniel K. Nishijima, Jonathan Schimmel, Alan B. Storrow, Nancy E. Wood, Venkatesh Thiruganasambandamoorthy, Christopher W. Baugh, Robert E. Weiss, Marc A. Probst

  • May 19, 2026

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