Incidence of anxiety disorders following Parkinson's disease: a population-based cohort study - Summary - MDSpire

Incidence of anxiety disorders following Parkinson's disease: a population-based cohort study

  • By

  • Bae, Youngoh

  • Han, Jongseung

  • Jeon, Sang Ryong

  • Shin, Wonsuk

  • Dong, Jae June

  • Jung, Hohyun

  • Lee, Seung Won

  • April 27, 2026

  • 0 min

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Objective:

To assess the incidence of anxiety disorders following a diagnosis of Parkinson's disease using a nationwide cohort.

Key Findings:
  • The incidence rate of anxiety disorder was 56.62 per 1,000 person-years in Parkinson's patients compared to 28.10 in controls.
  • The incidence rate ratio for anxiety disorder in Parkinson's patients was 2.01.
  • The increased risk of anxiety disorder was most pronounced in the first three years post-diagnosis and during long-term follow-up.
Interpretation:

Patients with Parkinson's disease have a significantly higher risk of developing anxiety disorders compared to the general population, indicating a need for ongoing mental health assessments.

Limitations:
  • The study may not account for all confounding factors influencing anxiety disorders.
  • Data is limited to a specific population in Korea, which may affect generalizability.
Conclusion:

Anxiety disorder is a critical non-motor symptom of Parkinson's disease, necessitating regular mental health monitoring in affected individuals.

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