To synthesize high-level evidence and define clinical, anatomical, and procedure-related predictors of seizures following endovascular aneurysm exclusion.
Approach:
Method: label
Method: text
Key Findings:
Hydrocephalus was most strongly associated with seizure occurrence (OR 3.91, 95% CI: 1.22 to 12.53).
Fisher grade 3 + 4 blood distribution was associated with seizures (OR 3.29, 95% CI: 1.55 to 6.97).
Hunt-Hess grade 1 to 3 showed a significant association with seizures (OR 3.15, 95% CI: 1.73 to 5.72).
WFNS grade 4 to 5 was associated with seizures (OR 1.86, 95% CI: 1.14 to 3.02).
Age, sex, middle cerebral artery involvement, and cerebral oedema were not statistically significant predictors.
Interpretation:
Greater radiological severity of hemorrhage, particularly dense subarachnoid blood, was linked to increased postoperative seizure likelihood; anatomical site and demographic characteristics showed no significant associations.
Limitations:
Observational designs and inconsistent definitions of seizure outcomes limited interpretation.
Moderate overall methodological quality as assessed by the Newcastle–Ottawa Scale.
Conclusion:
Results require cautious interpretation and may inform future risk stratification, but do not justify specific antiepileptic prophylaxis strategies.
