Port-site metastases after diagnostic laparoscopy in advanced ovarian cancer: a case report and a systematic review of the literature - Summary - MDSpire
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Port-site metastases after diagnostic laparoscopy in advanced ovarian cancer: a case report and a systematic review of the literature
To report a case of late-onset giant port-site metastasis (PSM) after diagnostic laparoscopy in advanced ovarian cancer and to conduct a systematic review of the literature on PSM incidence and management, highlighting the clinical implications of these findings.
Key Findings:
PSM incidence varies widely from 1.18% to 46.7% based on detection methods and study designs.
Risk factors for PSM include advanced FIGO stage, large-volume ascites, extensive peritoneal disease, and institutional expertise.
PSM does not independently affect overall survival but serves as a marker for aggressive disease.
Routine port-site resection can control local disease but increases wound-related morbidity without survival benefits.
Interpretation:
PSM following diagnostic laparoscopy in advanced ovarian cancer is more common than previously recognized, yet it does not significantly impact prognosis beyond the underlying disease severity, suggesting a need for careful monitoring.
Limitations:
The systematic review included only five studies, limiting the generalizability of findings and necessitating further research.
Variability in study designs and detection methods may affect reported incidence rates, highlighting the need for standardized approaches.
Conclusion:
While PSMs are frequent and can complicate management, diagnostic laparoscopy remains a safe and effective procedure when performed in specialized centers, with benefits outweighing the associated risks, underscoring the importance of careful patient selection.
by Orazio De Tommasi, Sofia Bigardi, Giosuè Giordano Incognito, Linda Modena, Chiara Goretti, Giulia Spagnol, Carla Ettore, Giuseppe Ettore, Marco Noventa, Carlo Saccardi, Roberto Tozzi
