Objective:

To assess anemia and related factors in patients with thyroid hormone dysfunction at the University of Gondar Comprehensive Specialized Hospital, highlighting the significance of these findings in the Ethiopian context.

Key Findings:

• Anemia prevalence among hypothyroid patients was 57.5% and 53.3% among hyperthyroid patients, with implications for treatment strategies.
• Types of anemia varied, including normochromic-normocytic, microcytic-hypochromic, and macrocytic normochromic, indicating diverse underlying mechanisms.
• Thyroid hormone dysfunction is linked to hematological abnormalities, significantly affecting erythropoiesis.

Interpretation:

The study highlights a significant prevalence of anemia in patients with thyroid dysfunction, indicating a critical need for comprehensive screening and management strategies in resource-limited settings like Ethiopia.

Limitations:

• The study is limited to a single hospital, which may affect the generalizability of the findings.
• Potential biases in self-reported data on behavioral characteristics.
• The cross-sectional design limits causal inferences.

Conclusion:

The findings underscore the importance of recognizing and addressing anemia in patients with thyroid dysfunction to improve patient outcomes, and further research is needed to explore this relationship.