Improvement of personality functioning in patients with personality disorders: a comparative study of mentalization-based treatment versus non-manualized treatments - Summary - MDSpire

Improvement of personality functioning in patients with personality disorders: a comparative study of mentalization-based treatment versus non-manualized treatments

  • By

  • Kjetil Bremer

  • Geir Pedersen

  • Andreas Ekberg

  • Katharina T. E. Morken

  • Helene A. Nissen-Lie

  • Eileen Oftedal

  • Theresa Wilberg

  • Elfrida. H. Kvarstein

  • June 22, 2026

  • 0 min

Share

Objective:

To investigate characteristics of patients admitted to mentalization-based treatment (MBT) versus non-manualized treatments (NMT), longitudinal changes in personality functioning (PF), and associations between initial personality disorder (PD) status and treatment outcomes.

Approach:
    Key Findings:
    • Patients in MBT had more severe personality pathology and a higher symptom burden compared to those in NMT.
    • Treatment condition explained little longitudinal variation, with comparable improvements in PF across both groups.
    • Effect sizes for improvement ranged from medium to large in both MBT and NMT.
    • Greater improvement in MBT was associated with an increasing number of borderline and narcissistic PD criteria.
    • Poorer improvement in MBT was linked to a higher number of avoidant PD criteria.
    Interpretation:

    Admittance to MBT versus NMT was largely matched to severity and type of PD.

    Limitations:
    • The study is observational and may not account for all variables influencing treatment outcomes.
    • The findings are based on data from a specific population in Norway, which may limit generalizability.
    Conclusion:

    Both MBT and NMT showed clinically relevant improvements. Further development of treatments for avoidant PD is necessary.

Original Source(s)

Related Content