Association of energy source with outcomes in en bloc TURB: secondary analysis of a randomized trial - Summary - MDSpire

Association of energy source with outcomes in en bloc TURB: secondary analysis of a randomized trial

  • By

  • Stefano Mancon

  • Francesco Soria

  • Rodolfo Hurle

  • Dmitry Enikeev

  • Evanguelos Xylinas

  • Lukas Lusuardi

  • Axel Heidenreich

  • Paolo Gontero

  • Eva Compérat

  • Shahrokh F. Shariat

  • David D’Andrea

  • March 27, 2025

  • 0 min

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Objective:

To evaluate the association of different energy sources used during en-bloc resection of bladder tumors (ERBT) with pathological findings and perioperative outcomes, emphasizing the significance of these findings for treatment decisions.

Key Findings:
  • DM was detected in 81% of patients and 80.6% of tumors resected.
  • Presence of DM was similar across energy modalities: 79% in b-ERBT, 83% in m-ERBT, and 83% in l-ERBT (p = 0.47).
  • Peri-operative outcomes varied by energy source, including operation duration and complication rates, but specific details were not provided.
Interpretation:

The study suggests that the choice of energy source during ERBT does not significantly affect the presence of DM in resected specimens, indicating similar quality of resection across modalities, which is crucial for accurate pathological assessment.

Limitations:
  • Limited evidence on the differential quality of resection based on energy source, which may affect clinical decision-making.
  • Potential biases in patient selection and reporting across centers could influence the generalizability of the findings.
Conclusion:

ERBT using different energy sources appears to yield comparable outcomes regarding the presence of DM, which is crucial for accurate pathological assessment and staging, highlighting the need for further research to confirm these findings.

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