To assess long-term (≥ 5 years) anthropometric and cardiometabolic outcomes among adolescents who underwent primary laparoscopic sleeve gastrectomy (LSG), highlighting the significance of these outcomes in managing severe obesity.
Key Findings:
Significant weight loss was observed at all follow-up points compared to preoperative values.
Cardiometabolic improvements included remission of T2DM, hypertension, and dyslipidemia over the 9-year period.
The study is the first to provide long-term data (≥ 5 years) on LSG outcomes in adolescents, indicating its potential as a viable treatment option.
Interpretation:
The findings suggest that LSG is effective in achieving sustained weight loss and improving cardiometabolic health in adolescents over a 9-year follow-up period, which may inform clinical practices in treating severe obesity.
Limitations:
Retrospective design may introduce selection bias, potentially affecting the generalizability of the results.
Data may not be generalizable to all adolescent populations due to specific inclusion criteria.
Conclusion:
LSG demonstrates durable benefits in weight loss and cardiometabolic health among adolescents, supporting its use as a treatment for severe obesity in this age group and contributing valuable long-term data to the existing literature.
A retrospective database study found a low absolute incidence but higher relative hazard of ischemic optic neuropathy following semaglutide initiation.