To identify clinical, pathological, and radiological parameters associated with extracapsular extension (ECE) in patients undergoing mpMRI prior to radical prostatectomy, highlighting their potential impact on treatment outcomes.
Key Findings:
Identified clinical, pathological, and mpMRI parameters significantly associated with ECE.
Inter-observer variability was assessed, indicating reliability in scoring.
The study provided insights into the predictive performance of various scoring systems.
Interpretation:
Multiparametric MRI is a valuable tool in predicting ECE, aiding in treatment planning and improving surgical outcomes.
Limitations:
Retrospective design may introduce selection bias.
Single-institution study limits generalizability.
Potential variability in radiologist interpretation despite training.
Conclusion:
mpMRI, combined with established scoring systems, enhances the prediction of ECE in prostate cancer, supporting better clinical decision-making.
by Francesco Sanguedolce, Alessandro Tedde, Luisa Granados, Jonathan Hernández, Jorge Robalino, Edgar Suquilanda, Matteo Tedde, Joan Palou, Alberto Breda