Laboratory Confirmation of Respiratory Syncytial Virus Infection Is Not Associated With an Increased Risk of Death in Adults With Acute Respiratory Illness - Summary - MDSpire

Laboratory Confirmation of Respiratory Syncytial Virus Infection Is Not Associated With an Increased Risk of Death in Adults With Acute Respiratory Illness

  • By

  • Jeffrey A Kline

  • Robert D Welch

  • Christopher Kabrhel

  • Daniel Mark Courtney

  • Carlos A Camargo

  • RESP-LENS site investigators

  • Michael J Roshon

  • Danielle E Turner-Lawrence

  • Michael A Puskarich

  • Ka Ming Gordon Ngai

  • Benton R Hunter

  • Joseph Bledsoe

  • James K d'Ettiene

  • Stephen S Lim

  • Christopher W Kabrhel

  • Esther J Choo

  • Steven M H Moore

  • Katherine R Buck

  • David M Beiser

  • James G Galbraith

  • Joby E Thoppil

  • Chris Kelly

  • Edward W Castillo

  • Israel E Green-Hopkins

  • Kristen S Nordenholz

  • Faheem C Guirgis

  • Bryan Wilson

  • Michael L Pulia

  • Stacey House

  • Justine M Pagenhardt

  • January 15, 2025

  • 0 min

Share

Objective:

To assess the association between RSV positivity and 30-day mortality and hospitalization in adults with acute respiratory illness presenting to emergency departments.

Key Findings:
  • 28.5% of adults with ARI underwent RSV testing, with a positivity rate of 2.4%.
  • Mortality rate for RSV+ adults was 1.9%, compared to 2.9% for RSV− adults.
  • Increased mortality was observed in RSV+ adults aged ≥65 years (3.8%).
  • RSV+ status was not associated with higher hospitalization or 30-day mortality rates, indicating a lack of correlation.
Interpretation:

Laboratory-confirmed RSV positivity in adults with ARI does not correlate with increased mortality risk, suggesting that other clinical factors may be more significant in determining outcomes and should be prioritized in clinical assessments.

Limitations:
  • The study is limited to data from emergency departments and may not represent all adult ARI cases.
  • Potential underreporting of RSV cases due to testing patterns and clinical practices may skew the understanding of RSV's impact.
Conclusion:

RSV positivity in adults with acute respiratory illness does not indicate a higher risk of hospitalization or death, emphasizing the need to consider other clinical factors in patient management.

Original Source(s)

Laboratory Confirmation of Respiratory Syncytial Virus Infection Is Not Associated With an Increased Risk of Death in Adults With Acute Respiratory Illness

  • by Jeffrey A Kline, Robert D Welch, Christopher Kabrhel, Daniel Mark Courtney, Carlos A Camargo, RESP-LENS site investigators, Michael J Roshon, Danielle E Turner-Lawrence, Michael A Puskarich, Ka Ming Gordon Ngai, Benton R Hunter, Joseph Bledsoe, James K d'Ettiene, Stephen S Lim, Christopher W Kabrhel, Esther J Choo, Steven M H Moore, Katherine R Buck, David M Beiser, James G Galbraith, Joby E Thoppil, Chris Kelly, Edward W Castillo, Israel E Green-Hopkins, Kristen S Nordenholz, Faheem C Guirgis, Bryan Wilson, Michael L Pulia, Stacey House, Justine M Pagenhardt

  • January 15, 2025

Related Content

Real-world Use of Molecular Point-of-care Testing for Sexually Transmitted Infections (STIs) in the Emergency Department: Why It Matters for Acute Care Management

FURL vs Mini-PCNL in 2 to 3 cm Stones

Review reports comparable stone-free rates with suction-assisted ureteroscopy

Mapping the therapeutic landscape in emergency incisional hernia: a scoping review