Development and validation of a prediction model for tuberculous peritoneal effusion - Summary - MDSpire

Development and validation of a prediction model for tuberculous peritoneal effusion

  • By

  • Libin Liu

  • Tingting Fang

  • Qianqian Peng

  • Hui Wei

  • Long Cai

  • June 19, 2026

  • 0 min

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Objective:

To develop and validate a nomogram for diagnosing tuberculous peritoneal effusion (TPE).

Approach:
    Key Findings:
    • A total of 351 patients were included, with 245 in the training group and 106 in the validation group.
    • Seven independent predictors identified: age, fever, ascites adenosine deaminase (ADA), ascites carcinoembryonic antigen (CEA), ascites total protein (TP), serum CEA, and serum creatinine (Cr).
    • The nomogram model achieved an AUC of 0.974 for the training group and 0.955 for the validation group.
    • Calibration curves showed good agreement, and decision curve analysis (DCA) indicated the model provides the greatest net benefit.
    Interpretation:

    Limitations:
    • Single-center study may limit generalizability.
    • Retrospective design may introduce selection bias.
    Conclusion:

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