The influence of C-reactive protein-triglyceride-glucose index (CTI) on the prognosis of heart failure patients with different ejection fractions - Summary - MDSpire
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The influence of C-reactive protein-triglyceride-glucose index (CTI) on the prognosis of heart failure patients with different ejection fractions
To assess the prognostic value of the C-reactive protein-triglyceride-glucose index (CTI) for all-cause mortality specifically in patients with chronic heart failure (CHF) across different ejection fraction (EF) subtypes.
Key Findings:
Patients with elevated CTI levels had a significantly higher risk of all-cause mortality compared to those with lower CTI levels, highlighting CTI's role as a prognostic marker.
Multivariable-adjusted Cox proportional hazards analysis confirmed that CTI levels were independently associated with increased all-cause mortality.
Elevated CTI levels were associated with higher all-cause mortality in patients with heart failure with reduced ejection fraction (HFrEF) and mildly reduced ejection fraction (HFmrEF).
Interpretation:
CTI is an independent prognostic marker for all-cause mortality in CHF patients across different EF subtypes.
Limitations:
The study was conducted at a single center, which may limit generalizability.
The observational nature of the study does not establish causation, and potential biases may affect the results.
Conclusion:
CTI may serve as a useful risk stratification biomarker for all-cause mortality in CHF patients, with implications for clinical practice.
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