Variations in Carotid Bulb Geometry Among Asian and Caucasian Populations - Summary - MDSpire

Variations in Carotid Bulb Geometry Among Asian and Caucasian Populations

  • By

  • Hossam Abdelmageed

  • Lamia Mbarek

  • Xuewei Xie

  • Yongjun Wang

  • Hui Li

  • Yang Liu

  • Huaguang Zheng

  • Robert Fleischmann

  • Jens P. Dreier

  • José Manuel Valdueza

  • April 21, 2026

  • 0 min

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Objective:

To examine ethnic differences in carotid bulb morphology between Asian and White individuals and its potential implications for atherosclerosis and ischemic stroke, particularly in understanding population-specific vascular anatomy.

Key Findings:
  • Significant ethnic differences in carotid bulb geometry were observed.
  • CB/ICA diameter was lower in Asian participants (1.57) compared to White participants (1.68; p < 0.001).
  • After adjustment, the difference in CB/ICA remained significant (−0.09; 95% CI -0.14 to −0.04; p < 0.001).
  • No significant interethnic difference in ICA diameter; carotid bulb diameter was smaller in Asian participants.
  • Adjusted differences were also noted for CB/CCA, ICA/CCA, and ECA/ICA.
Interpretation:

Differences in carotid bifurcation geometry between Asian and White adults may influence local hemodynamics, potentially affecting susceptibility to plaque formation and atherosclerosis.

Limitations:
  • Cross-sectional design limits causal inferences.
  • Study population may not represent all Asian and White individuals, particularly in terms of geographic and lifestyle factors.
Conclusion:

Carotid bifurcation geometry varies between Asian and White populations, which may have implications for understanding ethnic differences in atherosclerosis and stroke risk.

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