Association of the apolipoproteins with retinal arteriosclerosis in a health examination population - Summary - MDSpire

Association of the apolipoproteins with retinal arteriosclerosis in a health examination population

  • By

  • Xinghe Sun

  • Lijuan Guo

  • Hui Lv

  • Xian Zhang

  • Chaoqun Wu

  • Xiaohui Liu

  • June 17, 2026

  • 0 min

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Objective:

To investigate the relationship between apolipoproteins (ApoA1, ApoB, and ApoB/ApoA1 ratio) and retinal arteriosclerosis in a general health population.

Approach:
    Key Findings:
    • Retinal arteriosclerosis prevalence was 13.98% in males and 8.57% in females.
    • Individuals with retinal arteriosclerosis had significantly higher ApoB levels and ApoB/ApoA1 ratios.
    • In fully adjusted models, ApoB and ApoB/ApoA1 ratio were independently associated with retinal arteriosclerosis.
    • Significant associations were found in adults aged ≥45 years, non-smokers, and non-hypertensive individuals.
    Interpretation:

    Remove unsupported claims about the potential role in cardiovascular risk assessment.

    Limitations:
    • Cross-sectional design limits causal inferences.
    • Findings may not be generalizable beyond the studied population.
    Conclusion:

    Revise to reflect only the findings without suggesting implications.

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