International Federation for the Surgery and Other Therapies for Obesity (IFSO) global consensus recommendations for optimizing outcomes after sleeve gastrectomy - Summary - MDSpire

International Federation for the Surgery and Other Therapies for Obesity (IFSO) global consensus recommendations for optimizing outcomes after sleeve gastrectomy

  • By

  • Ricardo V Cohen

  • Mohammad Kermansaravi

  • Randy Levinson

  • Muffazal Lakdawala

  • Chetan Parmar

  • Yosuke Seki

  • Gerhard Prager

  • Paulina Salminen

  • members of the Global Consensus Recommendations for Optimizing Outcomes after Sleeve Gastrectomy

  • M Ackerman

  • N Alfaris

  • A Aly

  • A Aminian

  • S Aparicio

  • J Ard

  • C Boza

  • W Brown

  • B A Dayyeh

  • C Domene

  • M Felsenreich

  • K Gawdat

  • A Haddad

  • M Herrera

  • K Higa

  • K Kasama

  • L Kow

  • W J Lee

  • N D Lorenzo

  • S Mattar

  • A Miras

  • V Moize

  • A Nimeri

  • C Peng

  • A S Pernaute

  • R Peterli

  • T Petry

  • J Ponce

  • Y Preiss

  • N Reddy

  • R Rosenthal

  • S A Sabah

  • A Schroeder

  • A Shabbir

  • C Stier

  • October 15, 2025

  • 0 min

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Objective:

To develop evidence-based recommendations for managing suboptimal outcomes after sleeve gastrectomy (SG), particularly focusing on recurrent weight gain and gastro-oesophageal reflux disease (GORD) as critical factors for surgical success.

Key Findings:
  • Sleeve gastrectomy (SG) is the most performed metabolic bariatric surgery but may lead to suboptimal outcomes, including recurrent weight gain and GORD, which are critical for long-term success.
  • At 10 years, remission rates of type 2 diabetes (T2D) after SG varied significantly between studies, influenced by preoperative T2D duration, indicating the need for personalized approaches.
  • De novo GORD developed in 52% and 43% of patients in two major RCTs, with significant differences in oesophagitis prevalence compared to Roux-en-Y gastric bypass, underscoring the need for careful patient selection.
Interpretation:

Suboptimal outcomes post-SG are common and complex, necessitating tailored management strategies that consider individual patient profiles and further research to improve long-term results.

Limitations:
  • Evidence supporting strong clinical recommendations is heterogeneous and insufficient, which may limit the applicability of the guidelines.
  • The consensus focused on postoperative management, excluding preventive strategies during the primary procedure, which are also crucial for optimal outcomes.
Conclusion:

The guidelines emphasize the need for comprehensive management of postoperative complications and the importance of addressing both weight loss and obesity-related complications to enhance surgical success.

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