Invasive ventilation and association with outcomes in heart failure-related cardiogenic shock - Summary - MDSpire

Invasive ventilation and association with outcomes in heart failure-related cardiogenic shock

  • By

  • Lisa Besch

  • Caroline Kellner

  • Jonas Sundermeyer

  • Benedikt N. Beer

  • Angela Dettling

  • Marvin Kriz

  • Carsten Skurk

  • Peter Lüdike

  • Tienush Rassaf

  • Stefan Kluge

  • Holger Thiele

  • Alastair Proudfoot

  • Tobias Graf

  • Enzo Lüsebrink

  • Paulus Kirchhof

  • Stefan Blankenberg

  • Benedikt Schrage

  • June 15, 2026

  • 0 min

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Objective:

To evaluate the impact of invasive ventilation on outcomes in patients with heart failure-related cardiogenic shock across the severity of respiratory failure.

Approach:
    Key Findings:
    • 1010 patients were included, with 659 (65.2%) receiving invasive ventilation.
    • Invasive ventilation was associated with a prolonged ICU stay by 2.87 days compared to non-ventilated patients.
    • Patients with severe respiratory failure (PaO2/FiO2 ≤ 100) had an ICU stay extended by 3.83 days compared to non-ventilated patients.
    Interpretation:

    Limitations:
    • Retrospective design may introduce bias.
    • Exclusion of patients with acute myocardial infarction and other specific conditions limits generalizability.
    Conclusion:

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