The Impact of Preoperative Weight Loss on Long-term Success: 5-year Outcomes After Metabolic Bariatric Surgery - Summary - MDSpire
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The Role of Preoperative Weight Reduction in Long-term Outcomes: Five-Year Results Following Metabolic Bariatric Surgery

  • By

  • Kayleigh A. M. van Dam

  • Cathelijne Kam

  • Marijn T. F. Jense

  • Geert H. J. M. Verkoulen

  • Pieter P. H. L. Broos

  • Evelien de Witte

  • Jan Willem M. Greve

  • Evert-Jan G. Boerma

  • January 6, 2026

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Objective:

To evaluate the association between preoperative weight loss and total weight loss up to five years after metabolic bariatric surgery (MBS) and identify specific patient characteristics, such as age, gender, and comorbidities, associated with successful long-term weight loss outcomes.

Key Findings:
  • Patients with higher preoperative weight loss achieved greater total weight loss at 5 years, with statistical significance observed in %TWL across quartiles of preoperative weight loss.
  • Preoperative weight loss was associated with improved long-term outcomes.
Interpretation:

Preoperative weight loss may enhance long-term weight loss success after MBS, suggesting the importance of tailored preoperative strategies in patient management to optimize outcomes.

Limitations:
  • Retrospective design may introduce bias, potentially affecting the reliability of the findings.
  • Inconsistent definitions of preoperative weight loss in existing literature may complicate comparisons.
  • Limited follow-up duration in some studies restricts the ability to draw definitive conclusions.
Conclusion:

Preoperative weight loss is a significant predictor of long-term weight loss success after MBS, highlighting the need for tailored preoperative interventions.

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